Service

Introduction

Infections of research animals can often lead to subclinical diseases without visible clinical signs. In this state, transmission of the disease between the animals is possible. Furthermore, subclinical infections can cause effects and reactions in the organism, regarding e.g. the immune response, growth of the animal, behavior and so on. Depending on the use of the animals and the scope of research, these changes may have an impact on the experimental results, reproductive outcome, performance and other parameters.

Infections in the animals can also contaminate biological material such as transplant tumors, tissues, cell lines or sera with infectious agents. When these materials are used, also the pathogens can be transmitted.
Furthermore, some microorganisms are known as potential zoonotics and can be transmitted between animals and humans.

Based on this, a regular Health Monitoring of research animal facilities is recommended.
Please do not hesitate to contact us for support for an individual health monitoring program for your animal facility.

Analyses

  • Microbiological examination of different animal samples:
    – Parasitological analysis
    – Bacteriological analysis
    – Serological analysis
    – Molecularbiological analysis
  • Microbiological examination of biological material and fluids
  • Microbiological analysis of feed
  • Microbiological analysis of water
  • Sterility tests
  • Personnel control (e.g. stool samples)
  • Microbiological and molecularbiological analysis of environmental samples (e.g. from rooms, equipment, swabs, filters etc.)
  • Preparation of analytical reports

    Further analyses and special tests on request.

    Animal Species

    We provide analytical services for the following animal species:

    • Mice
    • Rats
    • Fishes
    • Guinea pigs
    • Rabbits
    • Dogs
    • Minipigs
    • Primates

    Further animal species on request.

    Analytical Material

    • Complete animal examination
    • Necropsy
    • Fecal samples
    • Blood/Serum samples
    • Dry Blood Spots
    • Swabs
    • Bedding
    • Exhaust air dust samples / filter samples
    • Cell lines
    • Sterility test material
    • Stool samples for personnel control
    • Rodac plates / environmental swabs

    Analyses of further material on request.

    Please contact us in advance for any analytical request.

    Please complete the analytical form, provided via our website or per email (contact details below).

    Please send the original of the analytical form together with the samples and as pdf per email.

    Analytical form EN 2019
    Analytical form Direct samples EN 2019
    Analytical form Fishes EN 2019

    Please contact our lab to arrange an appointed time before sending the material:

    Mrs. Romana Tomka
    +41 (0)61 416 96 15
    tomka@microbios.ch

     

    Sample Shipment

    The samples should be stored in the respective tubes. The tubes must be tightly closed. Dry Blood Spot cards should be dryed before closing. All samples must be clearly labelled.

    In general, direct samples of animals should be sent as soon as possible on the day of sample taking. When the shipment of samples on the same day is not possible, please store the direct samples as follows:

    Sample Storage conditions
    Feces samples PCR For a few hours cooled, overnight in the freezer (-20°C)
    Feces samples bacteriology Overnight in the refrigerator
    Pharynx swab PCR If not sent immediately, dry swab under sterile conditions approx. 2 hrs before placing in the tube; thereafter, store for a few hours or overnight in the refrigerator
    Pharynx swab bacteriology Overnight in the refrigerator
    Serum samples max. 1 day at room temperature, up to 5 days in the refrigerator, otherwise in the freezer (-20°C)
    DBS card After drying, store for a few days (max. one week) at room temperature; dry and clean conditions
    Sticky swab (fur) Overnight in the refrigerator

     

    For fresh samples with a short tansportation distance, shipment at room temperature is possible. Otherwise, the samples should be cooled during shipment.

    Biological material must be packed with three layers for shipment. This means that the tubes need to be wrapped with two additional materials, such as a second, bigger tube or a plastic bag which are than placed in a bubble-wrap envelope, or in case of higher sample numbers, in a styrofoam or cardboard box.

    Please always send the complete analytical form with the samples. The form is available on the homepage or can be sent to you per email, on request.

    To ensure fast processing of your samples, please contact MicroBioS in advance.

    Shipment address:
    MicroBioS GmbH
    Christoph Merian-Ring 31a
    CH – 4153 Reinach

    Contact for shipment of samples:
    tomka@microbios.ch
    +41 (0)61 416 96 15

    In case of enquiries, please do not hesitate to contact us.

    Analytical form EN 2019
    Analytical form Direct samples EN 2019
    Analytical form Fishes EN 2019

    Support

    We provide competent support and advice with focus on the following main topics:

    • relevant microorganisms in research animal facilities
    • analytical methods
    • health monitoring concepts

    Please do not hesitate to contact us for further enquiries.

    MicroBioS GmbH
    Christoph Merian-Ring 31A
    CH - 4153 Reinach

    +41 (0)61 416 96 10
    info@microbios.ch

    Management

    Dr. med. vet. Sandra Bäckert

    Dr. med. vet. Christina Simon
    Veterinary Specialist in Laboratory Animal Science